Ablative surgery for Parkinson disease

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Ablative surgery and deep brain stimulation for Parkinson's disease.

Surgical options for Parkinson's disease (PD) are rapidly expanding and include ablative procedures, deep brain stimulation, and cell transplantation. The target nuclei for ablative surgery and deep brain stimulation are the motor thalamus, the globus pallidus, and the subthalamic nucleus. Multiple factors have led to the resurgence of interest in the surgical treatment of PD: 1) recognition th...

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Complications of gamma knife surgery for Parkinson disease.

BACKGROUND Many medical centers throughout the world offer radiosurgery with the gamma knife (GK) for pallidotomy and thalamotomy as a safe and effective alternative to radiofrequency ablative surgery and deep brain stimulation for Parkinson disease (PD). The reported incidence of significant complications varies considerably, and the long-term complication rate remains unknown. DESIGN We des...

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Pathway for Parkinson disease.

Parkinson disease (PD) is a common neurodegenerative disease with unknown etiology. PD is commonly referred to as a “motor disease,” reflecting its clinical symptoms, including resting tremors of extremities, muscular rigidity, shuffling gait, stoop posture, and bradykinesia (1). The underlying pathology of PD is progressive neuronal loss, particularly in the substantia nigra pars compacta (SNc...

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Virtual visits for Parkinson disease

We sought to characterize recommendations and feedback of patients with Parkinson disease, each offered a free telemedicine consultation with a specialist. Visits consisted of history, neurologic examination, and recommendations. Midway through the program, patients were asked to complete an online satisfaction survey. From August 2012 to May 2013, 55 patients in 5 states (mean age 67.8 years) ...

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Surgical treatment for Parkinson disease

Since the beginning of neurosurgery, operations have been carried out throughout the central nervous system to treat movement disorders. In the 1930's and 1940's, early neurosurgical procedures focused on pyramidal tract lesions for tremor resolutions, but tremor reduction came only at the expense of motor weakness. The era of basal ganglia surgery for Parkinson's disease (PD) began when Meyers...

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ژورنال

عنوان ژورنال: Nature Reviews Neurology

سال: 2009

ISSN: 1759-4758,1759-4766

DOI: 10.1038/nrneurol.2009.44